DOTA
                        
                            
                                 
                            
                            
                            
                        
                        
                          
                    
                     
                            
                                DOTA 的全名是 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid,中文名称为 1,4,7,10-四氮杂环十二烷-四乙酸,其中 DO 是 dodecane 的前两个字母,TA 是 tetra acetic acid 中两个单词的首字母。DOTA 中的四个氮原子和以及氮原子上乙酸中的羧基可与金属配位,是一类常用的双功能螯合剂。
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                                DO-(CH2COOH)2
 
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                                DO-(CH2COONa)3
 
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                                DO-(CH2COOt-Bu)2
 
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                                DO-(CH2COOt-Bu)3
 
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                                DOTA-(CONH2)3
 
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                                DOTA-(COOt-Bu)3
 
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                                DOTA-(COOt-Bu)3-azide
 
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                                DOTA-(COOt-Bu)3-butyne
 
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                                DOTA-(COOt-Bu)3-C2-NH2
 
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                                DOTA-(COOt-Bu)3-C4-NH2
 
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                                DOTA-(COOt-Bu)3-CH2-Alkynyl
 
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                                DOTA-(COOt-Bu)3-CH2-Ph-azide
 
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                                DOTA-(COOt-Bu)3-Mal
 
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                                DOTA-(COOt-Bu)3-NHFmoc-Lys
 
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                                DOTA-(COOt-Bu)3-NHS
 
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                                DOTA-4AMP
 
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                                DOTA
 
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                                DOTA-Amide
 
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                                DOTA-azide
 
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                                DOTA-Acrylamide
 
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                                DOTA mono-NHS ester
 
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                                DOTA-butyne
 
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                                DOTA-Serotonin
 
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                                DOTA-SH
 
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                                DOTA-BCN
 
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                                DOTA-C2-NH2(TFA salt)
 
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                                DOTA-C4-NH2
 
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                                DOTA-CH2-Alkynyl (TFA salt)
 
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                                DOTA-CH2-Alkynyl(HCl salt)
 
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                                DOTA-CH2-Ph-azide (TFA salt)
 
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                                DOTA-CH2-Ph-azide(HCl salt)
 
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                                DOTA-DBCO
 
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                                DOTATATE
 
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                                DOTAGA2
 
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                                DOTAGA-(COOt-Bu)4
 
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                                (R)-DOTAGA-(COOt-Bu)4
 
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                                (S)-DOTAGA-(COOt-Bu)4
 
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                                DOTA-Maleimide
 
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                                DOTA-Tetrazine
 
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                                DOTA-MeTz
 
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                                DOTA-PEG4-MeTz
 
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                                DOTA-PEG8-NHCO-MeTz
 
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                                DOTA-PEG5-amine
 
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                                DOTA-PEG3-azide
 
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                                DOTA-PEG3-azide(HCl)
 
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                                DOTA-PEG5-azide
 
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                                DOTA-PEG5-C4-DBCO
 
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                                DOTA-p-NCS-Bn
 
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                                DOTA-p-NH2-Bn
 
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                                DOTA-p-NH2-Bn-(COOt-Bu)4
 
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                                DOTA-p-NH2-Bn-biotin
 
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                                DOTA-p-NO2-Bn
 
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                                DOT-Me-Acetic-acid
 
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                                DOTP
 
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                                p-NH2-Bn-oxo-DO3A
 
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                                p-SCN-Bn-oxo-DO3A
 
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                                (N3-PEG4)-(DOTA)-3K
 
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                                1,1',4,4',7,7'-Hexakis(1,1-dimethylethyl) 10,10'-[(5-nitro-1,3-phenylene)bis(methylene)]-Bis[DOTA-(COOt-Bu)3]
 
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                                1,4,7-Tris(1,1-dimethylethyl) 10-[2-[[3,5-bis(methoxycarbonyl)phenyl]amino]-2-oxoethyl]-[DOTA-(COOt-Bu)3]
 
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                                10,10'-[(5-Nitro-1,3-phenylene)bis(methylene)]-(DOTA)2  (HCl salt)
 
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                                10,10'-[(5-Nitro-1,3-phenylene)bis(methylene)]-(DOTA)2 (TFA salt)
 
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                                10-[2-[(3,5-Dicarboxyphenyl)amino]-2-oxoethyl]-DOTA (TFA salt)
 
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                                10-[2-[(3,5-Dicarboxyphenyl)amino]-2-oxoethyl]-DOTA(HCl salt)
 
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                                DOTA-tri(acid)-amido-PEG3-Bromoacetamide
 
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                                Cy7.5-CONH-(C1-CONH-C2-Mal)-C4-DOTA
 
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                                Bromoacetamido-PEG5-DOTA
 
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                                DOTA-(t-butyl)3-PEG5-azide
 
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                                DOTA-PEG5-amine HCl salt
 
客户近期使用本公司产品发表的高影响因子论文(IF>10)
- Amplifying antigen-induced cellular responses with proximity labelling
- Intelligent Nano-Cage for Precision Delivery of CRISPR-Cas9 and ACC Inhibitors to Enhance Antitumor Cascade Therapy Through Lipid Metabolism Disruption
- Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment
- A Versatile One-Step Enzymatic Strategy for Efficient Imaging and Mapping of Tumor-Associated Tn Antigen
- Surface-anchored tumor microenvironment-responsive protein nanogel-platelet system for cytosolic delivery of therapeutic protein in the post-surgical cancer treatment
- Genetically Incorporated Non-Canonical Amino Acids
- Boosting Dye-Sensitized Luminescence by Enhanced Short-Range Triplet Energy Transfer
- Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling
- Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling
- A proof-of-concept study on bioorthogonal-based pretargeting and signal amplify radiotheranostic strategy
- Bioengineered Platelets Combining Chemotherapy and Immunotherapy for Postsurgical Melanoma Treatment: Internal Core-Loaded Doxorubicin and External Surface-Anchored Anti-PDL1 Antibody Backpacks
- Scalable Synthesis of Highly Stable Cyclopropene Building Blocks: Application for Bioorthogonal Ligation with Tetrazines
- Noncanonical amino acids as doubly bio-orthogonal handles for one-pot preparation of protein multiconjugates
- Reversible control of tetrazine bioorthogonal reactivity by naphthotube-mediated host-guest recognition
- An Optimized Isotopic Photocleavable Tagging Strategy for SiteSpecific and Quantitative Profiling of Protein O‑GlcNAcylation in Colorectal Cancer Metastasis
 
            
 
   
   
             
        
 



 
        
 
        