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DOTA/NOTA/H3RESCA/MAG3/DTPA/Deferoxamine/NTA/Octaaminocryptands
DOTA/NOTA/H3RESCA/MAG3/DTPA/Deferoxamine/NTA/Octaaminocryptands
DOTA、NOTA、H3RESCA 等双功能螯合剂衍生物,用于医学诊疗试剂研发。
DOTA
DOTA 的全名是 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid,中文名称为 1,4,7,10-四氮杂环十二烷-四乙酸,其中 DO 是 dodecane 的前两个字母,TA 是 tetra acetic acid 中两个单词的首字母。DOTA 中的四个氮原子和以及氮原子上乙酸中的羧基可与金属配位,是一类常用的双功能螯合剂。
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DOTA
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DO-(CH2COOH)2
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DO-(CH2COONa)3
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DO-(CH2COOt-Bu)2
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DO-(CH2COOt-Bu)3
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DOTA-(CONH2)3
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DOTA-(COOt-Bu)3
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DOTA-(COOt-Bu)3-azide
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DOTA-(COOt-Bu)3-butyne
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DOTA-(COOt-Bu)3-C2-NH2
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DOTA-(COOt-Bu)3-C4-NH2
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DOTA-(COOt-Bu)3-CH2-Alkynyl
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DOTA-(COOt-Bu)3-CH2-Ph-azide
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DOTA-(COOt-Bu)3-Mal
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DOTA-(COOt-Bu)3-NHFmoc-Lys
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DOTA-(COOt-Bu)3-NHS
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DOTA mono-NHS ester
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DOTA-4AMP
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DOTA-Acrylamide
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DOTA-Amide
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DOTA-azide
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DOTA-DBCO
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DOTA-butyne
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DOTA-C4-NH2
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DOTA-CH2-Alkynyl (TFA salt)
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DOTA-CH2-Alkynyl(HCl salt)
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DOTA-CH2-Ph-azide (TFA salt)
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DOTA-CH2-Ph-azide(HCl salt)
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DOTAGA2
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DOTAGA-(COOt-Bu)4
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DOTA-Maleimide
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DOTA-MeTz
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DOTA-PEG3-azide
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DOTA-PEG3-azide(HCl)
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DOTA-PEG4-MeTz
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DOTA-PEG5-amine
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DOTA-PEG5-azide
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DOTA-PEG5-C4-DBCO
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DOTA-PEG8-NHCO-MeTz
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DOTA-p-NCS-Bn
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DOTA-p-NH2-Bn
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DOTA-p-NH2-Bn-(COOt-Bu)4
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DOTA-p-NH2-Bn-biotin
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DOTA-p-NO2-Bn
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DOTA-Serotonin
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DOTA-SH
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DOTATATE
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DOT-Me-Acetic-acid
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DOTP
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p-NH2-Bn-oxo-DO3A
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p-SCN-Bn-oxo-DO3A
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(N3-PEG4)-(DOTA)-3K
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(R)-DOTAGA-(COOt-Bu)4
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(S)-DOTAGA-(COOt-Bu)4
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1,1',4,4',7,7'-Hexakis(1,1-dimethylethyl) 10,10'-[(5-nitro-1,3-phenylene)bis(methylene)]-Bis[DOTA-(COOt-Bu)3]
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1,4,7-Tris(1,1-dimethylethyl) 10-[2-[[3,5-bis(methoxycarbonyl)phenyl]amino]-2-oxoethyl]-[DOTA-(COOt-Bu)3]
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10,10'-[(5-Nitro-1,3-phenylene)bis(methylene)]-(DOTA)2 (HCl salt)
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10,10'-[(5-Nitro-1,3-phenylene)bis(methylene)]-(DOTA)2 (TFA salt)
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10-[2-[(3,5-Dicarboxyphenyl)amino]-2-oxoethyl]-DOTA (TFA salt)
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10-[2-[(3,5-Dicarboxyphenyl)amino]-2-oxoethyl]-DOTA(HCl salt)
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DOTA-tri(acid)-amido-PEG3-Bromoacetamide
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Cy7.5-CONH-(C1-CONH-C2-Mal)-C4-DOTA
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DOTA-C2-NH2(TFA salt)
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DOTA-Tetrazine
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Bromoacetamido-PEG5-DOTA
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NOTA
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NOTA-(COOt-Bu)2
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NOTA-(COOt-Bu)2-Butyne
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NOTA-(COOt-Bu)3-Bn-NCS
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NOTA-(COOt-Bu)2-C4-NH2
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NOTA-Azide
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NOTA-Bn-Mal
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NOTA-Butyne
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NOTA-C6-amine
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NOTA-NHS ester
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(R)-NOTA-GA-(COOt-Bu)3
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NOTA-GA-Mal
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NOTA-Maleimide
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NOTA-PEG8-Mal
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NOTA-Tetrazine
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NOTA-Me-Tetrazine
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NOTA-PEG7-N3
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NOTA-PEG11-N3
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NOTA-CONH-PEG23-NH-CO-CH2-CH2-Mal
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NOTA-PEG5000-Mal
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NOTA-p-NCS-Bn
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NOTA-p-NH2-Bn
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NOTP
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NO-(COOt-Bu)2
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NODA-GA-NHS ester
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MeTz-PEG7-NOTA
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MeTz-PEG11-NOTA
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Me-Tetrazine-PEG11-NOTA
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2-[4-(2-hydroxyethyl)-1,4,7-triazonan-1-yl]ethan-1-ol
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NCS-MP-NODA
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3p-C-NETA-oxa-(tBu)-butanoic acid
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(S)-NOTA-GA-(COOt-Bu)3
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2C-p-NOTA-NCS
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p-NOTA-NCSA
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2C-p-NETA-NCS-Fmoc-D-赖氨酸
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NOTA-p-NCSA-amine-PEG8-azido
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NOTA-p-NCSA-DBCO-amine
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NOTA-p-NCSA-Fmoc-D-赖氨酸
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2p-C-NETA-NCS
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2C-p-NOTA-NCS-Fmoc-D-赖氨酸
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NOTA-p-NCSA-Me-Tetrazine-amine
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2C-p-NETA-NCS-amine-PEG8-azido
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2C-p-NOTA-NCS-amine-PEG8-azido
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2C-p-NETA-NCS-DBCO-amine
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2C-p-NETA-NCS-Me-Tetrazine-amine
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2C-p-NOTA-NCS-DBCO-amine
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2C-p-NOTA-NCS-Me-Tetrazine-amine
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2,2'-(7-(2-((3-(4-Carboxy-1H-1,2,3-triazol-1-yl)propyl)amino)-2-oxoethyl)-1,4,7-triazonane-1,4-diyl)diacetic acid
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10-[2-[(4-Hydroxy-4,4-diphosphonobutyl)amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid
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10-[2-Oxo-2-[[2-[(1-oxo-3,3-diphosphonopropyl)amino]ethyl]amino]ethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid
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10-[2-[(3,3-Diphosphonopropyl)amino]-2-oxoethyl]-1,4,7,10-tetraazacyclododecane-1,4,7-triacetic acid
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Hexahydro-α1-[3-[(4-hydroxy-4,4-diphosphonobutyl)amino]-3-oxopropyl]-1H-1,4,7-triazonine-1,4,7-triacetic acid
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Benzamide,N-(2-aminoethyl)-2,5-bis(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)-
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CB-Cyclam
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CB-TE2A
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DiAmSar
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p-NH2-Bn-PCTA
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p-SCN-Bn-HEHA
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p-SCN-Bn-PCTA
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p-SCN-Bn-TCMC
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1,4,8,11-Tetraazacyclotetradecane-1,4,8,11-tetraacetic acid
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2-(Benzoylthio)acetic acid
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AMD3100(双-1,4,8,11-四氮杂环十四烷-苯甲酰)-PEG2-Mal
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AMD3100(双-1,4,8,11-四氮杂环十四烷-苯甲酰)-PEG4-N3
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2,5-Bis(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)benzoic acid
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2,5-bis((4,8,11-tris(tert-butoxycarbonyl)-1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzoic acid
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